Glossary of HIV/AIDS Related Terms
(Starting with "O")
By
AIDSinfo,
Glossary of HIV/AIDS Related Terms, 5th Edition, AIDSinfo,
October 2005
ContactUs[at]aidsinfo.nih.gov
http://aidsinfo.nih.gov
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OAR
See: Office of AIDS
Research
OHL
See: Oral Hairy Leukoplakia
OIs
See: Opportunistic
Infections
Off-Label Use
Prescribed use of a medication for a condition other
than one approved by the Food and Drug Administration
(FDA), or for a patient population or at a dosage not
approved by the FDA.
Office of AIDS Research (OAR)
The office within the National Institutes of Health's
(NIH's) National Institute of Allergy and Infectious
Diseases (NIAID) responsible for the scientific, budgetary,
legislative, and policy elements of the NIH HIV/AIDS
research program.
Open-Label Trial
A clinical trial in which both the researchers and the
participants know who is getting which drug or vaccine.
See Also: Double-Blind
Study
Opportunistic Infections (OIs)
Illnesses caused by various organisms that occur in
people with weakened immune systems, including people
with HIV/AIDS. OIs common in people with AIDS include
Pneumocystis carinii pneumonia; cryptosporidiosis; histoplasmosis;
toxoplasmosis; other parasitic, viral, and fungal infections;
and some types of cancers.
Oral Hairy Leukoplakia (OHL)
A white-colored, hairy, or ribbed patch that appears
on the side of the tongue and inside the cheeks. It
develops mainly in people with weakened immune systems,
including people with HIV. It is caused by Epstein-Barr
virus (EBV), a member of the herpesvirus family.
Osteonecrosis
Also referred to as avascular necrosis. A medical condition
in which bone tissue dies. Osteonecrosis affects some
people with HIV, but it is unclear if it develops as
a complication of HIV infection or as a side effect
of anti-HIV drugs.
See Also: Avascular
Necrosis
Osteopenia
A medical condition in which bones lose their minerals
and become less dense, making them weaker and easier
to break.
Osteoporosis
Severe loss of bone mass, density, and strength. Although
usually an age-related disorder, osteoporosis may also
occur as a result of HIV infection or as a side effect
of anti-HIV drugs.
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